Exosomes in the field of skin care is an important recent trend that plays a key role in the future of regenerative medicine. Exosomes are primarily used in treatments such as lasers and microneedling to promote skin healing and improve the effectiveness of treatments. A new brand called SickScience has launched an exosome serum called ShapeShift V-Line Jaw Defining Serum that specifically targets stubborn fat under the chin. The serum, which retails for $58, shifts the application of exosomes to skin care and breaks new ground.
Dr. Merve Yildirim-Canpolat and Dr. Polen Koçak-Denizci, co-founders of the SickScience brand, met more than 10 years ago in a college chemistry class. They both have backgrounds in genetics and bioengineering, and have earned PhDs in biotechnology. While researching a treatment for a rare cancer, they discovered the potential of exosomes. Thus, the SickScience brand was born.
Exosome technology is a substance that acts as a communication tool between cells, which can also be referred to as a cell’s “youthful messenger.” Dr. Koçak-Denizci explains, “We studied exosomes from different sources, including human stem cells, and finally we started to study plant exosomes.” After 10 years of research, we created a biomimetic exosome technology called NX35, which uses exosomes of plant origin. Now we can alter the genome of exosomes to make them more targetable. In a way, we became the coders of this technology.
SickScience has developed its own exosome extraction technology to successfully isolate exosomes from plant cells.Dr. Koçak-Denizci adds, “We have also developed stabilization technology that allows exosomes to remain stable at room temperature for more than two years.”
ShapeShift V-Line Jaw Defining Serum is an application of the NX35 technology, which is primarily used in a contouring role.Dr. Koçak-Denizci explains, “ShapeShift works by redistributing lipid droplets without damaging the fat cells.” The goal is to reduce excess fat below the jawline as well as in other areas of the body. Typically, similar products only increase firmness or elasticity through peptides or caffeine, but this product works on a molecular level, impacting the fat itself. It was originally designed to make the jawline more prominent.
Dr. Yildirim-Canpolat adds, “We tested hundreds of exosomes to find the best option for this application.” Think of it as we have a library of exosomes, and we know the lipid and protein content of each exosome, as well as their function. The exosomes in this product come from pineapple stems. Other benefits include reducing wrinkles and creases and increasing skin moisture.
The jawline and chin area has long been a difficult area to care for, with traditional cosmetic treatments often failing to address excess fat below the jawline.The launch of ShapeShift V-Line Jaw Defining Serum offers a new solution to this problem.
The founders of the SickScience brand say their goal is to reshape the jawline by altering the distribution of fat cells through exosome technology. Unlike traditional products that can only improve the condition of the skin by increasing firmness or elasticity, ShapeShift V-Line Jaw Defining Serum works on the fat cells themselves to improve the underbelly of the jaw through molecular-level effects.
The product uses SickScience’s in-house developed biomimetic exosome technology, in which the exosomes are derived from plant cells. They selected the best exosomes for the application by carefully screening hundreds of exosomes. These exosomes have a specific lipid and protein composition, as well as a function to target fat under the chin. The exosomes used in the product are derived from pineapple stems, which offer a variety of benefits such as contouring, reducing wrinkles and increasing skin hydration.
Research and development by the SickScience team has allowed them to extract and stabilize exosomes from plant cells so that they can remain stable at room temperature for over two years. This provides assurance of the effectiveness of the product and the experience of using it.
The use of exosomes in skin care is an emerging trend that represents an important advancement in regenerative medicine, and SickScience’s ShapeShift V-Line Jaw Defining Serum offers an innovative solution to stubborn fat problems under the jawline through exosome technology. However, as with any new product or technology, consumers should carefully understand the product’s ingredients, application and possible results before using it, and consult a professional for advice if necessary.
